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UCSD Team Frees Protein Identification From
Database Searching Via 'Spectral Networks'

[April 6, 2007]

By Bernadette Toner

The UCSD approach does away with the database-searching step altogether by relying on the concept of spectral pairs: sets of spectra that occur naturally in most mass spec experiments as the result of overlapping peptides or from modified and unmodified versions of the same peptide.

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